How to manage fear is a cultural issue and most of people are unaware of it. They consider fear as the worst thing in the world and they try to avoid everything that could originate a doubt or a question or, even worst, lead to a 'dangerous' or risky situation. They're overwhelmed by fear and they don't live, just survive.
The second one is:
Twenty years from now you will be more disappointed by the things that you didn't do than by the ones you did do. So throw off the bowlines. Sail away from the safe harbor. Catch the trade winds in your sails. Explore. Dream. Discover.